José M Mato Selected Research

Peptides (Polypeptides)

9/2012	Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
3/2003	Functional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine.

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José M Mato Research Topics

Disease

28	Neoplasms (Cancer) 01/2021 - 08/2002
27	Fibrosis (Cirrhosis) 07/2023 - 02/2002
27	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 02/2002
24	Liver Neoplasms (Liver Cancer) 12/2023 - 04/2005
22	Non-alcoholic Fatty Liver Disease 07/2023 - 08/2002
19	Liver Diseases (Liver Disease) 01/2024 - 07/2002
17	Fatty Liver 01/2024 - 03/2003
10	Inflammation (Inflammations) 01/2022 - 07/2010
9	Carcinogenesis 01/2021 - 08/2002
9	Colonic Neoplasms (Colon Cancer) 01/2015 - 07/2007
8	Liver Cirrhosis (Hepatic Cirrhosis) 11/2020 - 07/2002
6	Cholestasis 02/2020 - 10/2012
5	Cholangiocarcinoma 01/2021 - 01/2017
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 10/2012
4	COVID-19 01/2022 - 01/2020
3	Infections 01/2022 - 01/2021
3	Obesity 06/2015 - 08/2002
3	Alcoholic Liver Diseases (Alcoholic Liver Disease) 10/2006 - 07/2002
2	Rare Diseases (Rare Disease) 12/2022 - 01/2021
2	Erythropoietic Porphyria (Congenital Erythropoietic Porphyria) 01/2021 - 01/2018
2	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 01/2018
2	Alcoholic Fatty Liver 08/2019 - 04/2010
1	Neoplasm Metastasis (Metastasis) 12/2023
1	Disease Progression 07/2023
1	Inborn Genetic Diseases (Disease, Hereditary) 12/2022
1	Atherosclerosis 12/2022
1	Acute Intermittent Porphyria (Porphyria, Acute) 11/2022
1	Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency) 11/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Tyrosinemias (Tyrosinemia) 02/2021

Drug/Important Bio-Agent (IBA)

35	S-Adenosylmethionine (Ademetionine)IBA 01/2024 - 02/2002
24	Methionine AdenosyltransferaseIBA 12/2023 - 08/2002
21	Proteins (Proteins, Gene)FDA Link 01/2024 - 03/2003
16	Methionine (L-Methionine)FDA Link 08/2019 - 07/2002
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2010
9	Messenger RNA (mRNA)IBA 01/2019 - 03/2002
8	EnzymesIBA 12/2022 - 11/2002
7	ProteomeIBA 02/2023 - 03/2003
7	Pemetrexed (MTA)FDA Link 01/2015 - 11/2004
6	Choline (Choline Chloride)IBA 01/2021 - 01/2003
6	Triglycerides (Triacylglycerol)IBA 09/2020 - 08/2002
6	Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)IBA 11/2019 - 04/2008
5	LipidsIBA 01/2024 - 08/2002
5	ProhibitinsIBA 12/2023 - 12/2010
4	CarbonIBA 12/2022 - 09/2011
4	Phosphotransferases (Kinase)IBA 01/2021 - 02/2009
4	MicroRNAs (MicroRNA)IBA 01/2021 - 11/2016
4	Fatty Acids (Saturated Fatty Acids)IBA 11/2019 - 07/2010
4	MitogensIBA 07/2013 - 03/2007
4	DNA (Deoxyribonucleic Acid)IBA 07/2010 - 04/2003
3	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022 - 01/2021
3	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2021
3	UbiquitinIBA 11/2020 - 01/2017
3	Glucose (Dextrose)FDA LinkGeneric 09/2020 - 09/2011
3	Glutathione (Reduced Glutathione)IBA 11/2016 - 08/2002
3	HomocysteineIBA 05/2011 - 07/2002
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2023 - 01/2008
2	Heme (Haem)IBA 11/2022 - 01/2018
2	ApolipoproteinsIBA 01/2022 - 01/2021
2	PorphyrinsIBA 01/2022 - 01/2020
2	Protons (Proton)IBA 01/2022 - 01/2018
2	acetoacetic acid (acetoacetate)IBA 02/2021 - 01/2016
2	aramcholIBA 09/2020 - 11/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2019 - 02/2012
2	Ethanol (Ethyl Alcohol)IBA 12/2019 - 01/2013
2	methylallyl trisulfide (MATS)IBA 08/2019 - 01/2018
2	VLDL LipoproteinsIBA 06/2019 - 03/2015
2	Sirtuin 1IBA 01/2019 - 08/2013
2	obeticholic acidIBA 12/2018 - 01/2018
2	CollagenIBA 12/2018 - 11/2012
2	pevonedistatIBA 01/2017 - 02/2015
2	Insulin-Like PeptidesIBA 11/2016 - 06/2011
2	Phosphatidylcholines (Phosphatidylcholine)IBA 06/2015 - 02/2015
2	AntigensIBA 11/2012 - 04/2012
2	Transaminases (Aminotransferases)IBA 10/2012 - 04/2008
2	Peptides (Polypeptides)IBA 09/2012 - 03/2003
2	5'-methylthioadenosineIBA 09/2012 - 07/2009
2	Insulin-Like Growth Factor I (IGF-1)IBA 06/2011 - 03/2002
2	MethyltransferasesIBA 07/2010 - 08/2009
2	LeptinIBA 03/2010 - 02/2008
2	Protein Isoforms (Isoforms)IBA 03/2008 - 12/2005
1	Matrix Metalloproteinase 7 (Matrilysin)IBA 12/2023
1	Matrix Metalloproteinases (MMPs)IBA 12/2023
1	ChromatinIBA 12/2023
1	Transcription Factors (Transcription Factor)IBA 12/2023
1	LuciferasesIBA 12/2023
1	ChemokinesIBA 12/2022
1	PorphobilinogenIBA 11/2022
1	Acute Hepatic PorphyriaIBA 11/2022
1	Phospholipases (Phospholipase)IBA 10/2022
1	very low density lipoprotein triglycerideIBA 10/2022
1	ribosomal protein L18IBA 01/2022
1	VaccinesIBA 01/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	ribosomal protein S3IBA 01/2022
1	fumarylacetoacetateIBA 02/2021
1	HydrolasesIBA 02/2021

Therapy/Procedure

5	Therapeutics 07/2023 - 04/2012
5	Chemoprevention 01/2018 - 07/2009
3	Ligation 01/2019 - 01/2018